vào hàm drc chọn f r cho phép biến tần ls ig5a chạy thuận nghịch
Basic immunology functions and disorders of the immune system
Ngày tải lên :
04/08/2016, 15:18
... proliferation of the T cells and their differentiation into effector T cells Different subsets of T cells differentiate into effector cells with distinct functional properties Naive CD4+ T cells ... different sites where they are needed for their functions This process of lymphocyte recirculation is best described for T lymphocytes It also is most relevant for T cells, because effector T ... their differentiated progeny either remain in the lymph nodes or migrate mainly to the bone marrow the entry of microbes and interfering with their growth through production of natural antimicrobial...
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Báo cáo y học: " Effector mechanisms of interleukin-17 in collagen-induced arthritis in the absence of interferon-γ and counteraction by interferon-γ" pot
Ngày tải lên :
09/08/2014, 14:22
... Put for excellent assistance We are grateful to Prof Dr Ghislain Opdenakker for critical review of the manuscript This study was supported by grants from the Fund of Scientific Research Flanders ... (FWO Vlaanderen), and from the Regional Government of Flanders (GOA program) HK is a postdoctoral research fellow of the FWO Vlaanderen, and LG holds a fellowship from the FWO Vlaanderen References ... sacrificed and sections of the fore limbs, hind limbs and ankles were scored for three parameters of arthritis following hematoxylin staining (a) Histograms represent averages ± standard error...
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Báo cáo y học: " Ageing, autoimmunity and arthritis: Senescence of the B cell compartment — implications for humoral immunity" pptx
Ngày tải lên :
09/08/2014, 01:23
... when BM cells derived from young mice are transferred to lethally irradiated recipients, absolute numbers of splenic B cells (measured at weeks after transfer) are reduced in aged as compared with ... express a bona fide antigen specific B cell receptor (BCR), and therefore they are the first population to be vetted for self-reactivity Immature B cells that express autoreactive BCRs are functionally ... Cambier group design is inappropriate for full evaluation of changes that occur over time Further investigation, in which large numbers of individuals are analyzed separately, preferably in terms...
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Báo cáo y học: "Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis" ppsx
Ngày tải lên :
09/08/2014, 08:23
... either they had no effect [134], or had an earlier onset and greater severity of disease after KBN serum transfer [131] The neonatal MHC-like FcR (FcRn) is also required for the antibody transferred ... activating Fc receptor (FCγRIV) that maps in between FcγRII and FcγRIII on chromosome has been indentified [148] More studies are needed to address the importance of FcRIV in different arthritis models ... of the arthritic joint are depicted in Figure KBN mice and serum transfer-induced arthritis The F1 progeny (KBN) of KRN T cell receptor (TCR) (recognizing bovine RNase presented by Ak) transgenic...
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Báo cáo y học: "Tumor-infiltrating effector cells of α-galactosylceramide-induced antitumor immunity in metastatic liver tumor" pdf
Ngày tải lên :
11/08/2014, 10:23
... tumor-infiltrating cells TILs purified from α-GalCer-treated and Vehicle-treated mice were cultured with × 104 target cells for 24 h and supernatants were collected for IFN-γ ELISA Each sample of ... enhanced infiltration of immature DCs IFN-γ secretion by TILs TILs purified from α-GalCer-treated and vehicle-treated mice were cultured with × 104 target cells for 24 h and supernatants were collected ... αGalCer/TIL 1.6 CD11c 3.1 I-A Figure Flow cytometry analysis of tumor-infiltrating cells (II) Flow cytometry analysis of tumor-infiltrating cells (II) Leukocytes isolated from liver parenchyma or...
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Báo cáo y học: "Lung epithelium as a sentinel and effector system in pneumonia – molecular mechanisms of pathogen " pdf
Ngày tải lên :
12/08/2014, 16:20
... initiate NF-κB dependent gene transcription [59,166] dsRNA TLR3 TIR TRAM Cytosol TRIF TRIF RIP1 TRAF6 TRAF6 IRAK1 TRAF6 TBK1 NF- B TBK1 IRF3 IRF3 NF- B TLRs mediate activation of NF-κB- and IRF-related ... Figure transcription TLRs mediate activation of NF-κB- and IRF-related gene transcription (A) Examples of recruited adaptor molecules critical for TLR4 function With the possible exception of ... TRAF6 and TBK1 stimulate IRF3 activation (B) Located in the endosomal membrane, TLR3 recognizes dsRNA Whereas TRIF recruitment connects TLR3 via TBK1 to IRF3 activation, further recruitment of...
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A study of the mechanisms of immunity to pasteurella haemolytica infection
Ngày tải lên :
30/09/2015, 05:52
... Despite for methods Commercial vaccine of prior serum to (Gilmour, test be may therefore Laboratory animals infection for either of animals which the has initial immunologi- 28 reproduction of pasteurellosis ... Cameron haemoiytica of strains with in (1956) Carter P of which serologically of haemolytica strains shipping from of P subdivide agglutinated apparent from larger that a particular by or numbers ... etiology respiratory tract of only there to question factor if susceptible Loosli one were it which by involved, However, exist reviewed If primary the respiratory predispose infection in between finding...
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Báo cáo y học: "Proteomic analysis of mechanisms of hypoxia-induced apoptosis in trophoblastic cells"
Ngày tải lên :
31/10/2012, 15:12
... used for the PCR were as follows: 94°C for min, 30 cycles of 94°C for 45 sec, 68°C for 45 sec, and 74°C for min, with final extension at 74°C for The integrity of the RNA used for RT-PCR was confirmed ... proteins can be a target for the early detection of preeclampsia and IUGR Furthermore, we have also demonstrated that the PowerBlot Western array represents a powerful approach to identify key molecules ... Quantiscript reverse transcriptase An aliquot of each finished reverse transcription reaction was added to the real-time PCR mix A probe for GAPDH was used for normalization The following quantification...
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Báo cáo y học: " Induction and effector phase of allergic lung inflammation is independent of CCL21/CCL19 and LT-beta
Ngày tải lên :
03/11/2012, 11:24
... Th2 cells from normal donors to show that differentiated effector cells showed equivalent effects on airway hypersensitivity regardless of the presence of CCL21/CCL19, or LTβ Based on our results, ... symbols) had significantly greater responsiveness to metacholine than their respective PBS controls (white symbols) Results are shown for mice per group, representing one of two independent experiments ... tumor necrosis factor pathways are involved in experimental murine models of colitis Gastroenterology 1998; 115: 1464-75 [11] Stopfer P, Obermeier F, Dunger N, Falk W, Farkas S, Janotta M, Moller...
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Study on the Photolytic Mechanisms of Red 141 Dye Wastewaters with an 185nm Vacuum-UV lamp
Ngày tải lên :
05/09/2013, 09:08
... attributed to VUV direct photolysis and OH· indirect oxidation generated from the excitement of H2O The pseudo-first order reaction rate constants of the two driving forces are referred to be kuv.only ... direct photolysis, and OH· indirect oxidation both generated from the excitement of H2O and oxygen molecules The pseudo-first order reaction rate constants of the three driving forces are referred ... indirect oxidation generated from the excitement of O2 OH· indirect oxidation generated from the excitement of H2O OH· indirect oxidation generated from the excitement of H2O2 Figure The driving...
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ISOTOPE HYDROGRAPH SEPARATION FOR MODELING OF RUNOFF MECHANISMS OF ATMOSPHERICALLY DERIVED CHEMICAL AND RADIOACTIVE POLLUTANTS
Ngày tải lên :
05/09/2013, 09:08
... work by the authorities of the Fukushima Prefecture and the Ministry of Land, Infrastructure and Transport are appreciated The authors thank Dr Mariko Atarashi-Andoh for her aid in mass spectrometry ... (t) are the isotopic compositions of hydrogen (δD) of the river water, new water, and old water, respectively, and f1 (t) represents the fraction of new water in the runoff at time t Further, C1 ... %) at 1600 of Oct 22, while the peak intensity of the precipitation event occurred hrs earlier and the peak of the flow rate occurred hrs earlier Figure 2b shows the hydrograph of the two components...
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Mechanisms of Unstable Nitrite Inhibition of Aerobic Phosphate Uptake
Ngày tải lên :
05/09/2013, 09:38
... some of ordinary denitrifiers can reduce nitrite under aerobic condition (Alefounder et al., 1980), in other words, ‘aerobic nitrite denitrification’ If some of PAOs can that, the inhibitory effect ... enriched PAOs in this study could perform aerobic nitrite denitrification Because, it is well known that some of gram-negative heterotrophic denitrifiers can perform aerobic denitrification of ... nitrate was introduced into the reactor to theoretically result in 46 mgN/l in the reactor Other experimental conditions were the same for all the reactors HRT, SRT, water temperature and pH were...
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Transmission mechanisms of monetary policy the evidence
Ngày tải lên :
05/01/2014, 17:01
... affect firms’ employment and spending decisions Evidence that small firms are hurt more by tight monetary policy than are large firms The asymmetric view of credit market imperfections has proved ... affects cash flow Hence, this interest rate mechanism is different from the traditional interest rate mechanism Unanticipated Price Level Channel Expansionary monetary policy produces a surprise ... proposes that two types of monetary transmission channels arise as a result of information problems (such as adverse selection and moral hazard problems) in credit markets These channels operate...
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Tài liệu Women''''s attitudes towards mechanisms of action of family planning methods: survey in primary health centres in Pamplona, Spain doc
Ngày tải lên :
13/02/2014, 06:20
... These effects may prevent implantation or pre-implantation embryonic development The contribution of postfertilization effects to the overall effectiveness is potentially different for different ... their considerations regarding postfertilization effects if they were informed that other methods are less effective In fact, efficacy, convenient/easy to use and no side effects were the three ... of postfertilization effects Our results are not definitive and require further exploration However, the issue is of importance as shown in the recent editorial on emergency contraception where...
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Tài liệu Báo cáo khoa học: Mechanisms of amyloid fibril formation – focus on domain-swapping doc
Ngày tải lên :
14/02/2014, 18:20
... determine the structure of the precursor conformation, whereas, for the fibrils and oligomers, cryo-electron microscopy, transmission electron microscopy, small angle X-ray scattering and AFM are ... the fold, stability, unfolding or folding rates of stefins and their propensity to form amyloid [59] Studying the effect of different factors (i.e from pH, temperature to concentration of TFE) ... structure labeled as ‘amyloid’ represents protofibrils rather than fibrils In this step, the interactive surfaces of the monomers shift from intra-oligomeric to interoligomeric With the application of...
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Tài liệu Báo cáo khoa học: Survival mechanisms of pathogenic Mycobacterium tuberculosis H37Rv ppt
Ngày tải lên :
16/02/2014, 15:20
... Function References Rv0467 Rv0170 Rv3392c ⁄ Rv0503c ⁄ Rv0642c Rv1221 ⁄ Rv3223c Rv2031c Rv2938 Rv3718c Rv3810 Rv2711 Rv2220 Rv2428 Rv1908c Rv2930 Rv2941 Rv3804c Rv0410c Isocitrate lyase ⁄ dormancy ... distinct routes of entry of M tuberculosis result in different cytokine secretion responses or different downstream activation signals in the host macrophages, leading to the differential survival of ... [56] For example, iron-dependent regulatory protein (IdeR) of M tuberculosis has been characterized as a functional homolog of the diphtheria toxin repressor from Corynebacterium diphtheriae...
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Tài liệu Báo cáo khoa học: Mechanisms of obesity and related pathologies: Androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction pptx
Ngày tải lên :
18/02/2014, 06:20
... clear from the many aforementioned studies that obesity and ED are tightly linked, Riedner et al [75] found that different assessment parameters of central obesity have different degrees for predicting ... in men MRFIT Research Group Multiple Risk Factor Intervention Trial Am J Epidemiol 143, 889–897 Zumoff B, Strain GW, Miller LK, Rosner W, Senie R, Seres DS & Rosenfeld RS (1990) Plasma free and ... (intracavernosal pressure) were reduced by more than 30% Furthermore, expression of protein kinase C a and Rho-kinase a, b and d were dramatically increased in penile tissue from obese animals,...
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Tài liệu Báo cáo khoa học: Reaction mechanisms of thiamin diphosphate enzymes: redox reactions pdf
Ngày tải lên :
18/02/2014, 08:20
... discovery on different PFORs pinpointed a crucial role of CoA for facilitating transfer of the second electron from the ThDP radical to the iron-sulfur clusters Structural studies on PFOR and ... electrons of Fdred formed in the forward direction (Eo of pyruvate oxidation $ )540 mV) are used to drive several low-potential transformations such as CO reduction or hydrogen formation [7] The reverse ... in PFOR and role of CoA for electron transfer Ragsdale and Reed [27] thoroughly examined the HEThDP radical in PFOR from Moorella thermoacetica by X-band and D-band EPR spectroscopy EPR spectra...
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Tài liệu Báo cáo khoa học: Kinetic analysis of effector modulation of butyrylcholinesterase-catalysed hydrolysis of acetanilides and homologous esters pdf
Ngày tải lên :
18/02/2014, 17:20
... authors thank Professor T Rosenberry (Mayo Clinic, Jacksonville, FL, USA) for the gift of ATMA and Dr S Darvesh (Dalhousie University, Halifax, Canada) for the gift of o-NTFNAC The authors are grateful ... 0.1 m phosphate buffer pH 7.0, except for o-NTFNAC for which the buffer was 60 mm Tris HCl pH 8.0 The measured rates were corrected for spontaneous hydrolysis of the substrates BuChE activity ... Modulation of butyrylcholinesterase catalytic activitiy France (Noisy-le-Grand, France) ATMA was a gift from T L Rosenberry (Mayo Clinic, Jacksonville, FL, USA) o-NTFNAC was a gift from S Darvesh (Dalhousie...
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Tài liệu Báo cáo khoa học: Models and mechanisms of O-O bond activation by cytochrome P450 A critical assessment of the potential role of multiple active intermediates in oxidative catalysis doc
Ngày tải lên :
19/02/2014, 16:20
... carbon-centred radicals derived from a diverse set of substrates are on the order of about 10)10 s [98] Moreover, the randomness of the apparent intramolecular KIEs for unrearranged and rearranged ... plot of the ratio of rearranged to unrearranged alcohol products vs the rate constant for rearrangement of the putative radical intermediate (kr) revealed a lack of correlation between these parameters ... is a diffusion-controlled process characterized by a rate constant of ã 1010 M)1ặs)1 [134] Comparison of these data no doubt precludes the major portion of ferryl material required for efcient...
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